This question is a bit like asking if you know whether the sky is blue. Of course you know a ministry leader couple who could use a retreat specifically designed to encourage them! The Haft, situated in the Northern Poconos, is running just such a retreat for no more than 7 pastor/leader couples on October 2-4, 2012.
I have had a part of developing this retreat format and highly recommend it for anyone who might wish to catch their breath with a few other like-minded couples. Going doesn’t mean you are burned out (though you might be) or that you are on the verge of collapse (though you might be). Going means you want to sustain your ministry trajectory.
Check out the link above to see more information about the location and some great pics of the place. I’ve been there a couple of times and find the buildings and the surrounding countryside very refreshing. Even if you are unable to attend this event, you can work with them to set up your own personal retreat.